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COX2/Cyclooxygenase 2 Mouse mAb
一鍵復(fù)制產(chǎn)品信息
EM1160
規(guī)格： 價格：
50μL ￥1280.00
100μL ￥1980.00

Overview

Product name: COX2/Cyclooxygenase 2 Mouse mAb
Reactivity: Human, Rat, Mouse
Alternative Names: PTGS2 antibody, Prostaglandin H2 synthase 2 antibody, PGHS 2 antibody, Glucocorticoid-regulated inflammatory cyclooxygenase antibody
Source: Mouse
Dilutions: IHC?1:100-200
Immunogen: Synthetic Peptide
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles.
Clonality: Monoclonal
Isotype: IgG1
Concentration: 1mg/mL
Observed Band: 70kDa
GeneID: 5743
Human Swiss-Prot No: P35354
Cellular localization: Endoplasmic reticulum,?Membrane,?Microsome
Background: Prostaglandin-endoperoxide synthase 2, also known as cyclooxygenase-2 or simply COX-2, is an enzyme that in humans is encoded by the PTGS2 gene. There are two isozymes of COX encoded by distinct gene products: a constitutive COX-1 (this enzyme) and an inducible COX-2, which differ in their regulation of expression and tissue distribution. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors. A splice variant of COX-1 termed COX-3 was identified in the CNS of dogs, but does not result in a functional protein in humans. Two smaller COX-1-derived proteins (the partial COX-1 proteins PCOX-1A and PCOX-1B) have also been discovered, but their precise roles are yet to be described.
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