黄色网站看片欧美-成人大片男人的天堂-女人被免费看在线看-在线观看视频一区网-日日摸日日添日日透 情久久国产视频网站上,青青青国产在线视频在线观看,久久99中文字幕久久,亚洲不卡免费视频

產(chǎn)品中心

Bag-4 rabbit pAb
一鍵復制產(chǎn)品信息
ES1745
規(guī)格： 價格：
50μL ￥1280.00
100μL ￥1980.00

Overview

Product name: Bag-4 rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: BAG4; SODD; BAG family molecular chaperone regulator 4; BAG-4; Bcl-2-associated athanogene 4; Silencer of death domains
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen: Synthesized peptide derived from the C-terminal region of human Bag-4.
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 50kD
GeneID: 9530
Human Swiss-Prot No: O95429
Cellular localization: Cytoplasm.
Background: The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. This protein was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3), and thereby negatively regulates downstream cell death signaling. The regulatory role of this protein in cell death was demonstrated in epithelial cells which undergo apoptosis while integrin mediated matrix contacts are lost. Alternatively spliced transcript variants encoding distinct
關閉

在線咨詢

Online consultation

  • 在線咨詢
  • 技術支持

關注微信公眾號

微信掃一掃立即咨詢

微信掃一掃立即咨詢

關閉