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BMP-2 rabbit pAb
一鍵復(fù)制產(chǎn)品信息
ES1775
規(guī)格: 價(jià)格:
50μL ¥1280.00
100μL ¥1980.00

Overview

Product name: BMP-2 rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: BMP2; BMP2A; Bone morphogenetic protein 2; BMP-2; Bone morphogenetic protein 2A; BMP-2A
Source: Rabbit
Dilutions: IF: 1:50-200 Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human BMP-2. AA range:226-275
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 60kD
GeneID: 650
Human Swiss-Prot No: P12643
Cellular localization: Secreted.
Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients. [provided by RefSeq, Jul 2016],
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