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產(chǎn)品中心

DnaJB4 rabbit pAb

一鍵復(fù)制產(chǎn)品信息

ES2187

規(guī)格：	價格：
50μL	￥1280.00
100μL	￥1980.00

下載說明 ①

Overview

Product name:	DnaJB4 rabbit pAb
Reactivity:	Human;Mouse;Rat
Alternative Names:	DNAJB4; DNAJW; HLJ1; DnaJ homolog subfamily B member 4; Heat shock 40 kDa protein 1 homolog; HSP40 homolog; Heat shock protein 40 homolog; Human liver DnaJ-like protein
Source:	Rabbit
Dilutions:	Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen:	The antiserum was produced against synthesized peptide derived from human DNAJB4. AA range:91-140
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	38kD
GeneID:	11080
Human Swiss-Prot No:	Q9UDY4
Cellular localization:	Cytoplasm . Cell membrane . Cytoplasmic according to PubMed:18837411 and membrane-associated according to PubMed:16542645.
Background:	The protein encoded by this gene is a molecular chaperone, tumor suppressor, and member of the heat shock protein-40 family. The encoded protein binds the cell adhesion protein E-cadherin and targets it to the plasma membrane. This protein also binds incorrectly folded E-cadherin and targets it for endoplasmic reticulum-associated degradation. This gene is a strong tumor suppressor for colorectal carcinoma, and downregulation of it may serve as a good biomarker for predicting patient outcomes. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015],

Western Blot analysis of various cells using DnaJB4 Polyclonal Antibody
Immunohistochemical analysis of paraffin-embedded Human brain. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by i
Western blot analysis of lysates from HepG2 cells, using DNAJB4 Antibody. The lane on the right is blocked with the synthesized peptide.

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