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產(chǎn)品中心

Ku-86 rabbit pAb

一鍵復(fù)制產(chǎn)品信息

ES2685

規(guī)格：	價格：
50μL	￥1280.00
100μL	￥1980.00

下載說明 ①

Overview

Product name:	Ku-86 rabbit pAb
Reactivity:	Human;Rat;Mouse;
Alternative Names:	XRCC5; G22P2; X-ray repair cross-complementing protein 5; 86 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 2; ATP-dependent DNA helicase II 80 kDa subunit; CTC box-binding factor 85 kDa subunit; CTC85; CTCBF; DNA repair pr
Source:	Rabbit
Dilutions:	Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen:	The antiserum was produced against synthesized peptide derived from human XRCC5. AA range:441-490
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	80kD
GeneID:	7520
Human Swiss-Prot No:	P13010
Cellular localization:	Nucleus . Nucleus, nucleolus . Chromosome .
Background:	The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008],

Western Blot analysis of various cells using Ku-86 Polyclonal Antibody
Western Blot analysis of A549 cells using Ku-86 Polyclonal Antibody
Immunohistochemical analysis of paraffin-embedded Human brain. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by i
Western blot analysis of lysates from Jurkat cells, using XRCC5 Antibody. The lane on the right is blocked with the synthesized peptide.

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