MTNR1B; Melatonin receptor type 1B; Mel-1B-R; Mel1b receptor
Source:
Rabbit
Dilutions:
WB 1:500-2000;IHC-p 1:50-300
Immunogen:
The antiserum was produced against synthesized peptide derived from human MTR1B. AA range:301-350
Storage:
-20°C/1 year
Clonality:
Polyclonal
Isotype:
IgG
Concentration:
1 mg/ml
Observed Band:
40kD
GeneID:
4544
Human Swiss-Prot No:
P49286
Cellular localization:
Cell membrane; Multi-pass membrane protein.
Background:
This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This gene product is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin. [provided by RefSeq, Jul 2008],