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MLTK rabbit pAb
一鍵復制產品信息
ES2801
規(guī)格: 價格:
50μL ¥1280.00
100μL ¥1980.00

Overview

Product name: MLTK rabbit pAb
Reactivity: Human;Mouse
Alternative Names: MLTK; ZAK; HCCS4; Mitogen-activated protein kinase kinase kinase MLT; Human cervical cancer suppressor gene 4 protein; HCCS-4; Leucine zipper- and sterile alpha motif-containing kinase; MLK-like mitogen-activated protein triple kinase; Mixe
Source: Rabbit
Dilutions: WB 1:500-2000;IHC-p 1:50-300
Immunogen: The antiserum was produced against synthesized peptide derived from human MLTK. AA range:701-750
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 91kD
GeneID: 51776
Human Swiss-Prot No: Q9NYL2
Cellular localization: Cytoplasm . Nucleus . Translocates to the nucleus upon ultraviolet B irradiation. .
Background: This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],
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