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MMP-13 rabbit pAb
一鍵復(fù)制產(chǎn)品信息
ES2804
規(guī)格: 價格:
50μL ¥1280.00
100μL ¥1980.00

Overview

Product name: MMP-13 rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: MMP13; Collagenase 3; Matrix metalloproteinase-13; MMP-13
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. IF 1:100-300 Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human MMP-13. AA range:10-59
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 55kD
GeneID: 4322
Human Swiss-Prot No: P45452
Cellular localization: Secreted, extracellular space, extracellular matrix . Secreted .
Background: This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. Mutations in this gene are associated with metaphyseal anadysplasia. This gene is part of a cluster of MMP genes on chromosome 11. [provided by RefSeq, Jan 2016],
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