MRPL3; MRL3; RPML3; 39S ribosomal protein L3; mitochondrial; L3mt; MRP-L3
Source:
Rabbit
Dilutions:
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Immunogen:
Synthesized peptide derived from MRP-L3 . at AA range: 20-100
Storage:
-20°C/1 year
Clonality:
Polyclonal
Isotype:
IgG
Concentration:
1 mg/ml
Observed Band:
38kD
GeneID:
11222
Human Swiss-Prot No:
P09001
Cellular localization:
Mitochondrion .
Background:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L3P ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 13q. [provided by RefSeq, Jul 2008],