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MSH3 rabbit pAb
一鍵復(fù)制產(chǎn)品信息
ES2857
規(guī)格: 價(jià)格:
50μL ¥1280.00
100μL ¥1980.00

Overview

Product name: MSH3 rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: MSH3; DUC1; DUG; DNA mismatch repair protein Msh3; hMSH3; Divergent upstream protein; DUP; Mismatch repair protein 1; MRP1
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human MSH3. AA range:51-100
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 127kD
GeneID: 4437
Human Swiss-Prot No: P20585
Cellular localization: nuclear chromosome,nucleoplasm,membrane,MutSbeta complex,
Background: The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3-7 repeats have been reported. Defects in this gene are a cause of susceptibility to endometrial cancer. [provided by RefSeq, Mar 2011],
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