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NEIL3 rabbit pAb
一鍵復(fù)制產(chǎn)品信息
ES2917
規(guī)格: 價格:
50μL ¥1280.00
100μL ¥1980.00

Overview

Product name: NEIL3 rabbit pAb
Reactivity: Human;Mouse
Alternative Names: NEIL3; Endonuclease 8-like 3; DNA glycosylase FPG2; DNA glycosylase/AP lyase Neil3; Endonuclease VIII-like 3; Nei-like protein 3
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human NEIL3. AA range:491-540
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 35kD
GeneID: 55247
Human Swiss-Prot No: Q8TAT5
Cellular localization: Nucleus . Chromosome . Recruited to replication stress sites via interaction with ubiquitinated CMG helicase. .
Background: NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226]).[supplied by OMIM, Mar 2008],
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