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CD63 rabbit pAb
一鍵復(fù)制產(chǎn)品信息
ES4255
規(guī)格： 價格：
50μL ￥1280.00
100μL ￥1980.00

Overview 文獻(xiàn)(2)

Product name: CD63 rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: CD63; MLA1; TSPAN30; CD63 antigen; Granulophysin; Lysosomal-associated membrane protein 3; LAMP-3; Melanoma-associated antigen ME491; OMA81H; Ocular melanoma-associated antigen; Tetraspanin-30; Tspan-30; CD63
Source: Rabbit
Dilutions: IF: 1:50-200 Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human CD63. AA range:121-170
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 26,35-65(kD
GeneID: 967
Human Swiss-Prot No: P08962
Cellular localization: Cell membrane ; Multi-pass membrane protein . Lysosome membrane ; Multi-pass membrane protein . Late endosome membrane ; Multi-pass membrane protein . Endosome, multivesicular body . Melanosome . Secreted, extracellular exosome . Cell surface . Also found in Weibel-Palade bodies of endothelial cells (PubMed:10793155). Located in platelet dense granules (PubMed:7682577). Detected in a subset of pre-melanosomes. Detected on intralumenal vesicles (ILVs) within multivesicular bodies (PubMed:21962903). .
Background: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Apr 2012],
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