The antiserum was produced against synthesized peptide derived from human RFTN1. AA range:432-481
Storage:
-20°C/1 year
Clonality:
Polyclonal
Isotype:
IgG
Concentration:
1 mg/ml
Observed Band:
65kD
GeneID:
23180
Human Swiss-Prot No:
Q14699
Cellular localization:
Cell membrane ; Lipid-anchor . Cytoplasm . Membrane raft . Endosome . Early endosome . Translocates from cytoplasm to cell membrane where it colocalizes with poly (I:C) and then moves to endosomes where it colocalizes with TLR3 (PubMed:21266579). Translocates from cytoplasm to cell membrane where it colocalizes with TLR4 and then together with TLR4 moves to endosomes, upon lipopolysaccharide stimulation (PubMed:27022195). .
Background:
function:May play a pivotal role in the formation and/or maintenance of lipid rafts. May regulate B-cell antigen receptor-mediated signaling.,similarity:Belongs to the raftlin family.,subcellular location:Associates with lipid rafts.,tissue specificity:Specifically expressed by B-cells (at protein level).,