黄色网站看片欧美-成人大片男人的天堂-女人被免费看在线看-在线观看视频一区网-日日摸日日添日日透 情久久国产视频网站上,青青青国产在线视频在线观看,久久99中文字幕久久,亚洲不卡免费视频

產(chǎn)品中心

Flt-3 (phospho Tyr842) rabbit pAb
一鍵復(fù)制產(chǎn)品信息
ES5321
規(guī)格： 價格：
50μL ￥1280.00
100μL ￥1980.00

Overview

Product name: Flt-3 (phospho Tyr842) rabbit pAb
Reactivity: Human;Mouse
Alternative Names: FLT3; CD135; FLK2; STK1; Receptor-type tyrosine-protein kinase FLT3; FL cytokine receptor; Fetal liver kinase-2; FLK-2; Fms-like tyrosine kinase 3; FLT-3; Stem cell tyrosine kinase 1; STK-1; CD antigen CD135
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human FLT3 around the phosphorylation site of Tyr842. AA range:808-857
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 170kD
GeneID: 2322
Human Swiss-Prot No: P36888
Cellular localization: Membrane; Single-pass type I membrane protein. Endoplasmic reticulum lumen. Constitutively activated mutant forms with internal tandem duplications are less efficiently transported to the cell surface and a significant proportion is retained in an immature form in the endoplasmic reticulum lumen. The activated kinase is rapidly targeted for degradation.
Background: This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia. [provided by RefSeq, Jan 2015],
關(guān)閉

在線咨詢

Online consultation

  • 在線咨詢
  • 技術(shù)支持

關(guān)注微信公眾號

微信掃一掃立即咨詢

微信掃一掃立即咨詢

關(guān)閉