GALR1; GALNR; GALNR1; Galanin receptor type 1; GAL1-R; GALR-1
Source:
Rabbit
Dilutions:
Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Immunogen:
The antiserum was produced against synthesized peptide derived from human GALR1. AA range:161-210
Storage:
-20°C/1 year
Clonality:
Polyclonal
Isotype:
IgG
Concentration:
1 mg/ml
Molecular Weight:
39kD
GeneID:
2587
Human Swiss-Prot No:
P47211
Cellular localization:
Cell membrane; Multi-pass membrane protein.
Background:
The neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart. [provided by RefSeq, Jul 2008],